ESPCI web site
Nanopore technologies allow high-throughput sequencing of long strands of DNA at the cost of a relatively large error rate. This limits its use in the reading of amplicon libraries in which there are only a few mutations per variant and therefore they are easily confused with the sequencing noise. Consensus calling strategies reduce the error but sacrifice part of the throughput on reading typically 30 to 100 times each member of the library.
GIGASCIENCE
By: Rocío Espada, Nikola Zarevski, Adèle Dramé-Maigné, Yannick Rondelez .
Published:09 November 2022
DOI: https://academic.oup.com/gigascienc...