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  • Coupling Exponential to Linear Amplification for Endpoint Quantitative Analysis

    Exponential DNA amplification techniques are fundamental in ultrasensitive molecular diagnostics. These systems offer a wide dynamic range, but the quantification requires real-time monitoring of the amplification reaction. Linear amplification (...)


  • In Vitro Enzyme Self-Selection Using Molecular Programs

    Directed evolution provides a powerful route for in vitro enzyme engineering. State-of-the-art techniques functionally screen up to millions of enzyme variants using high throughput microfluidic sorters, whose operation remains technically (...)


  • Dynamical order and many-body correlations in zebrafish show that three is a crowd

    Zebrafish constitute a convenient laboratory–based biological system for studying collective behavior. It is possible to interpret a group of zebrafish as a system of interacting agents and to apply methods developed for the analysis of systems (...)


  • Odd elasticity and topological waves in active surfaces

    Odd elasticity describes active elastic systems whose stress-strain relationship is not compatible with a potential energy. As the requirement of energy conservation is lifted from linear elasticity, new antisymmetric (odd) components appear in (...)


  • Noise-induced collective actuation in active solids

    Collective actuation describes the spontaneous synchronized oscillations taking place in active solids when the elasto-active feedback, which generically couples the reorientation of the active forces and the elastic stress, is large enough. In (...)


  • Does the Larkin length exist?

    The yield stress of random solid solutions is a classic theme in physical metallurgy that currently attracts a renewed interest in connection to high entropy alloys. Here, we revisit this subject using a minimal dislocation dynamics model, (...)


  • Martingale drift of Langevin dynamics and classical canonical spin statistics

    A martingale is a stochastic process that encodes a kind of fairness or unbiasedness, which is associated with a reference process. Here we show that, if the reference process xt evolves according to the Langevin equation with drift a(x) and if (...)


  • Spontaneous self-constraint in active nematic flows

    Active processes drive biological dynamics across various scales and include subcellular cytoskeletal remodelling, tissue development in embryogenesis and the population-level expansion of bacterial colonies. In each of these, biological (...)


  • Non-Gaussian fluctuations of a probe coupled to a Gaussian field

    The motion of a colloidal probe in a complex fluid, such as a micellar solution, is usually described by the generalized Langevin equation, which is linear. However, recent numerical simulations and experiments have shown that this linear (...)


  • Damping-Driven Time Reversal for Waves

    Damping is usually associated with irreversibility. Here, we present a counterintuitive concept to achieve time reversal of waves propagating in a lossless medium using a transitory dissipation pulse. Applying a sudden and strong damping in a (...)


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